2021

Colon cancer cells acquire immune regulatory molecules from tumor-infiltrating lymphocytes by trogocytosis

Jae Hun Shin, Jaekwang Jeong, Stephen E. Maher, Heon-Woo Lee, Jaechul Lim, Alfred L. M. Bothwell
PMC Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640789/

2019

Dickkopf-2 regulates the stem cell marker LGR5 in colorectal cancer via HNF4α1

Jae Hun Shin, Jaekwang Jeong, Jungmin Choi Jaechul Lim, Ravi K. Dinesh, Jonathan Braverman, Jun Young Hong, Stephen E. Maher, Maria C. Amezcua Vesely, WonJu Kim, Ja-Hyun Koo, Wenwen Tang, Dianqing Wu, Holly N. Blackburn, Rosa M. Xicola, Xavier Llor, Omer Yilmaz, Je-Min Choi, and Alfred L.M. Bothwell
PMC Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099562/

Functional diversity of MDSCs: the multitasking Hydra of cancer

Asha Jayakumar and Alfred. L. M. Bothwell
PMC Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703177/

Dickkopf1: An immunomodulatory ligand and Wnt antagonist in pathological inflammation

Wook-Jin Chae, Alfred L.M. Bothwell
PMC Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982462/

RIPK3-Induced Inflammation by I-MDSCs Promotes Intestinal Tumors

Asha Jayakumar, Alfred L.M. Bothwell
PMC Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395226/

2018

Canonical and Non-Canonical Wnt Signaling in Immune Cells

Wook-Jin Chae, Alfred L.M. Bothwell
PMC Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367500/

Regulation of human T cell responses by dNP2-ctCTLA-4 inhibits human skin and microvessel graft rejection

Sangho Lim, Nancy C. Kirkiles-Smith, Jordan S. Pober, Alfred L.M. Bothwell, Je-Min Choi
PMC Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141312/

Therapeutic Potential of Gene-Modified Regulatory T Cells: From Bench to Bedside

Wook-Jin Chae, Alfred L. M. Bothwell
PMC Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820299/

DKK2 imparts tumor immunity evasion through ß-catenin-independent suppression of cytotoxic immune cell activation

Qian Xiao, Jibo Wu, Wei-Jia Wang, Shiyang Chen, Yingxia Zheng, Xiaoqing Yu, Katrina Meeth, Mahnaz Sahraei, Alfred L. M. Bothwell, Lieping Chen, Marcus Bosenberg, Jianfeng Chen, Veronika Sexl, Le Sun, Lin Li, Wenwen Tang, Dianqing Wu
PMC Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840007/